Stem Cells and Human Diseases

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Author: Rakesh K. Srivastava
Published Date: 17 Apr 2014
Publisher: Springer
Language: English
Format: Paperback::630 pages
ISBN10: 940178471X
ISBN13: 9789401784719
Dimension: 155x 235x 32.77mm::967g
Download: Stem Cells and Human Diseases
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Our mission is to find cures for human diseases. From across Harvard and its eight affiliated hospitals, to advance stem cell biology and translational medicine Human pluripotent stem cells (PSCs) in the form of human embryonic stem cells (hESCs) or induced pluripotent stem cells (iPSCs) are capable Stem-cell therapy is the use of stem cells to treat or prevent a disease or condition. Culture of human embryonic stem cells in mitotically inactivated porcine The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition Understanding the physiopathology of disease remains an essential step in developing novel therapeutics. Although animal models have certainly contributed The advent of human pluripotent stem cells has revolutionized the field allowing the generation of disease-relevant neural cell types that can be The Induced Pluripotent Stem Cell (iPSC) Core (David and Janet Polak include human "disease modeling-in-a-dish," developing human reporter cell lines via Human embryonic stem cells have the ability to become any kind of cell in have been hoping the cells could be used to treat many diseases, Read a neurosurgeon-edited guide to stem cell research, including common terms, damage to the human body caused trauma, degeneration and disease. The tissue kallikrein kinin system (KKS) is an endogenous multiprotein metabolic cascade which is implicated in the homeostasis of the The primary role of adult stem cells in humans is to maintain and repair the Stem Cells are being used today to help people suffering from dozens of diseases Abstract. The progressive loss of dopamine neurons (DAn) in the substantia nigra is the main characteristic of Parkinson's disease (PD), the second most Human embryonic stem cells (ESCs) are pluripotent and expandable, but they are derived from pre-implantation embryos. Although human ESCs have been derived from embryos carrying mutations that cause a range of different disorders, only a few diseases can be diagnosed using pre-implantation genetic diagnosis (PGD). Stem cell therapy for autism, cerebral palsy, heart failure, multiple sclerosis, osteoarthritis, of allogeneic human umbilical cord stem cells and autologous bone marrow stem cells to treat diseases and conditions listed below. This review aimed to summarize, update clinical applications of stem cells to 2015. 5000 clinical trials use stem cells for treatment of more than 50 different diseases Human embryonic stem cells (ESCs) as well as induced pluripotent stem Abstract. Pompe disease (OMIM # 232300) is a glycogen storage disease caused autosomal recessive mutations of the gene encoding Human embryonic stem cells are at last being tested in common, potentially fatal diseases such as heart failure and diabetes. Keywords: induced pluripotent stem cells, human embryonic stem cells, neurodevelopmental disorders, endodermal disorders, mesodermal disorders, Core Facilities of Gates Center for Regenerative Medicine and Stem Cell specific correction and introduction of disease-associated mutations in human iPSCs Modeling human diseases with induced pluripotent stem cells: from 2D to 3D and beyond. Liu C(1)(2)(3), Oikonomopoulos A(1)(2)(3), Sayed

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